Biocompatible functionalisation of starch.

نویسندگان

  • Apostolos Alissandratos
  • Nina Baudendistel
  • Bernhard Hauer
  • Kai Baldenius
  • Sabine Flitsch
  • Peter Halling
چکیده

The enzyme catalysed esterification of starch and fatty acids with terminal triple bonds is described. This material can be used as an acceptor for azide containing molecules, through azide/alkyne cycloaddition. The potential is illustrated by the production of fluorescently-labelled starch, and a biotinylated derivative which can bind streptavidin.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A short review on Ferrofluids surface modification by natural and biocompatible polymers

This paper provides an overview of how the surface properties of ferromagnetic nanoparticles dispersed in fluids is modified by natural and biocompatible polymers. Among common magnetic nanoparticles, magnetite (Fe3O4) and maghemite (g-Fe203) are popular candidates because of their biocompatibility. Natural polymeric coating materials are the most commonly used biocompatible magnetic nanopartic...

متن کامل

Industrial bioprocesses and biocatalysis Lectures L1.1 Enzymatic acylation of starch

Starch is an interesting, natural, abundant and renewable raw material. For many applications, its properties can be improved by chemical modification, and acylation has been commonly used. Traditionally this makes use of powerful acylating agents (anhydrides and acid chlorides) and/or harsh conditions. Enzymatic acylation would be attractive because of the use of mild conditions, specific reac...

متن کامل

Evaluation of Biopolymers Effect on In vitro Biocompatibility Property of Nano Hydroxyl Apatite Composites

In this work, we report the effect of biopolymers (starch and gelatin) on in vitro biocompatibility property of nano hydroxyapatite (nHAp) composites. Cell culture and MTT assays were performed for in vitro biocompatibility. They show that nHAp can affect the proliferation of cells and the nHAp-starch and nHAP-gelatin biocomposites have no negative effect on the cell morphology, viability and p...

متن کامل

Evaluation of Biopolymers Effect on In vitro Biocompatibility Property of Nano Hydroxyl Apatite Composites

In this work, we report the effect of biopolymers (starch and gelatin) on in vitro biocompatibility property of nano hydroxyapatite (nHAp) composites. Cell culture and MTT assays were performed for in vitro biocompatibility. They show that nHAp can affect the proliferation of cells and the nHAp-starch and nHAP-gelatin biocomposites have no negative effect on the cell morphology, viability and p...

متن کامل

Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components

BACKGROUND Gold nanoparticles (AuNPs) are a popular choice for use in medical and biomedical research applications. With suitable functionalisation AuNPs can be applied in drug delivery systems, or can aid in disease diagnosis. One such functionalisation is with chitosan, which enables efficient interaction and permeation of cellular membranes, providing an effective adjuvant. As both AuNPs and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 47 2  شماره 

صفحات  -

تاریخ انتشار 2011